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Sebastian Wachsmann Hogiu

Academic title(s): 

Professor

Undergraduate Program Director

Sebastian Wachsmann Hogiu
Contact Information
Email address: 
sebastian.wachsmannhogiu [at] mcgill.ca
Phone: 
514.398.1520
Office: 
McConnell聽Engineering Building, Room 362
Degree(s): 

BSc: Bucharest University, Physics, Biophysics

PhD: Humboldt University, Berlin, Experimental Physics,

PostDoc: Carnegie Mellon University, Pittsburgh, Chemical Physics

Previous Appointments: Carnegie Mellon University, Pittsburgh; Cedars Sinai Medical Center, Los Angeles; University of California Davis, Davis; Intellectual Ventures / Global Good, Seattle

Areas of interest: 
  • Biosensors
  • Biomimetics
  • Point of need and wearable technologies
  • Quantum Biology
Courses: 
  • BIEN 210: Electrical and Optical Properties of Optical Systems
  • BIEN 390: Bioengineering Laboratory
  • BIEN 560: Design of Biosensors
Selected publications: 
  1. Adam Melnyk, Lena Kozarov, Sebastian Wachsmann-Hogiu, 鈥 A deconvolution approach to modelling surges in COVID-19 cases and deaths鈥, Scientific Reports, 13 (1), 2361.
  2. Meruyert Imanbekova, Ayse Mine Saridag, Mehmet Kahraman, Juanjuan Liu, Humeyra Caglayan, and Sebastian Wachsmann-Hogiu, 鈥淐omplementary Metal Oxide Semiconductor Based Sensing Platform for Trapping, Imaging, and Chemical Characterization of Biological Samples鈥. ACS Applied Optical Materials, 2022, .
  3. Juanjuan Liu, Sebastian Wachsmann-Hogiu, 鈥淧rogress and Challenges of Point of Need Photonic Biosensors for the Diagnosis of COVIDS-19 Infections and Immunity鈥, Biosensors, 2022,
  4. Meruyert Imanbekova, Sorina Suarasan, Yao Lu, Sarah Jurchuk, Sebastian Wachsmann-Hogiu, 鈥淩ecent advances in label-free characterization of extracellular vesicles鈥, Nanophotonics, 04/2022.
  5. Reza Abbasi, Juanjuan Liu, Sorina Suarasan, Sebastian Wachsmann-Hogiu, 鈥淪E-ECL on a CMOS: a miniaturized electrochemiluminescence system鈥, Lab on a Chip, 02/2022.
  6. Juanjuan Liu, Roozbeh Siavash Moakhar, Sara Mahshid, Fartash Vasefi, Sebastian Wachsmann-Hogiu, 鈥淢ultimodal electrochemical and SERS platform for chlorphenapyr detection鈥, Applied Surface Science, 2021, Vol 566, pp. 150617.
  7. Meruyert Imanbekova, Sorina Suarasan, Tatu Rojalin, Rachel Mizenko, Silvia Hilt, Meghna Mathur, Paula Lepine, Michael Nicouleau, Nguyen-Vi Mohamed, Thomas Durcan, Randy Carney, John Voss, Sebastian Wachsmann-Hogiu, 鈥淚dentification of amyloid beta in small extracellular vesicles via Raman spectroscopy鈥, Nanoscale Advances, 2021, 3, 4119-4132.
  8. Juanjuan Liu, Mahsa Jalali, Sara Mahshid, Sebastian Wachsmann-Hogiu, "Are plasmonic optical biosensors ready for use in point-of-need applications?", Analyst, 2020, Vol. 145, pp. 364-384.
  9. Sorina Suarasan, Juanjuan Liu, Meruyert Imanbekova, Tatu Rojalin, Silvia Hilt, John C Voss, Sebastian Wachsmann-Hogiu, "Superhydrophobic bowl-like SERS substrates patterned from CMOS sensors for extracellular vesicle characterization", Journal of Materials Chemistry B, 2020, Vol. 8, pp. 8845-8852.
  10. Juanjuan Liu, Roozbeh Siavash Moakhar, Ayyappasamy Sudalaiyadum Perumal, Horia Nicolae Roman, Sara Mahshid, Sebastian Wachsmann-Hogiu, "A AgNP-deposited commercial electrochemistry test strip as a platform for urea detection", Scientific Reports, 2020, Vol 10, pp. 1-11.
  11. Meruyert Imanbekova, Ayyappasamy Sudalaiyadum Perumal, Sara Kheireddine, Dan V Nicolau, Sebastian Wachsmann-Hogiu, 鈥淟ensless, reflection-based dark-field microscopy (RDFM) on a CMOS chip", Biomedical Optics Express, 2020, Vol. 11, pp. 4942-4959.
  12. Sebastian Wachsmann-Hogiu, Zachary J Smith, Mehmet Kahraman, 鈥溾, Frontiers in Chemistry, 2019, 7, pp.865
  13. Sara Kheireddine, Zachary J Smith, Dan V Nicolau, Sebastian Wachsmann-Hogiu, 鈥溾, Biomedical optics express, 2019, 10(9), pp. 4369-4380.
  14. Sara Kheireddine, Ayyappasamy Sudalaiyadum Perumal, Zachary J. Smith, Dan V. Nicolau, and Sebastian Wachsmann-Hogiu, Dual-Phone Illumination-Imaging System for High Resolution and Large Field of View Multi-Modal Microscopy, Lab on a Chip, 2019.
  15. Korkmaz, M. Kenton, G. Aksin, M. Kahraman, S. Wachsmann-Hogiu, 鈥淚nexpensive and flexible substrates on adhesive tape based on biosilica plasmonic nanocomposites鈥, ACS Applied Nano Materials, 2018/8/17.
  16. Rebeca Ferraz de Menezes, Catherine Malinda Harvey, Marleny Elizabeth M谩rquez de Mart铆nez Gerbi, Zachary J Smith, Dan Smith, Juan C Ivaldi, Alton Phillips, James W Chan, Sebastian Wachsmann-Hogiu, 鈥淔s-laser ablation of teeth is temperature limited and provides information about the ablated components鈥 Journal of Biophotonics 05/2017;, DOI:10.1002/jbio.201700042
  17. Mehmet Kahraman, Emma R. Mullen, Aysun Korkmaz, Sebastian Wachsmann-Hogiu, 鈥淔undamentals and applications of SERS-based bioanalytical sensing鈥, Nanophotonics 01/2017; 6(5)., DOI:10.1515/nanoph-2016-0174.
  18. Ruby K. Gill, Zachary J. Smith, Changwon Lee, and Sebastian Wachsmann-Hogiu, 鈥The effects of laser repetition rate on femtosecond laser ablation of dry bone: a thermal and LIBS study鈥, Journal of Biophotonics, 9 (1-2), 171-180, 2016.
  19. Tingjuan Gao, Zachary Smith, Tzu-yin Lin, Danielle Carrade Holt, Stephen M Lane, Dennis L Matthews, Denis M Dwyre, James Hood, Sebastian Wachsmann-Hogiu, 鈥濃, Analytical chemistry 87 (23), 11854-11862, 2015.
  20. Ruby K Gill, Zachary J Smith, Ripul R Panchal, John W Bishop, Regina Gandour-Edwards, Sebastian Wachsmann-Hogiu, , Biomedical Optics Express, 6 (12), 4850-4858, 2015.
  21. Kaiqin Chu, Zachary J. Smith, Sebastian Wachsmann-Hogiu, 鈥淒eveloping an inexpensive blood imaging system: where are we now?鈥, Expert Review of Medical Devices. 12(5), 613-627, 2015.
  22. Changwon Lee, Randy P. Carney, Sidhartha Hazari, Zachary Smith, Alisha Knudson, Christopher S. Robertson, Kit S. Lam and Sebastian Wachsmann-Hogiu*, 鈥3D plasmonic nanobowl platform for the study of exosomes in solution鈥, Nanoscale, 2015, DOI: 10.1039/C5NR01333J.
  23. Zachary J Smith, Changwon Lee, Tatu Rojalin, Randy P Carney, Sidhartha Hazari, Alisha Knudson, Kit Lam, Heikki Saari, Elisa Lazaro Iba帽ez, Tapani Viitala, Timo Laaksonen, Marjo Yliperttula, Sebastian Wachsmann-Hogiu, , Journal of Extracellular Vesicles, 5, 2015
  24. Changwon Lee, Christopher S. Robertson, An H. Nguyen, Mehmet Kahraman, Sebastian Wachsmann-Hogiu, 鈥Thickness of a metallic film, in addition to its roughness, plays a significant role in SERS activity鈥, online, Scientific Reports 5, 2015
  25. Ralph Green, Sebastian Wachsmann-Hogiu, 鈥淒evelopment, history, and future of automated cell counters鈥, Clinics in Laboratory Medicine, 35, 2015, pp. 1-10.
  26. Mehmet Kahraman, Sebastian Wachsmann-Hogiu, 鈥淟abel-Free and Direct Protein Detection on 3D Plasmonic Nanovoid Structures using Surface-Enhanced Raman Scattering鈥, Analytica Chimica Acta, 856, 2015, pp. 74-81.
  27. R. K. Gill, F. Knorr, Z. J. Smith, M. Kahraman, D. Madsen, D. S. Larsen, S. Wachsmann-Hogiu, 鈥淐haracterization of Femtosecond Laser Induced Breakdown Spectroscopy (fsLIBS) and Applications for Biological Samples鈥, Applied Spectroscopy, Vol. 68, 9, 2014, pp. 949-54
  28. Z. J. Smith, T. Gao, K. Chu, S. M. Lane, D. L. Matthews, D. M. Dwyre, J. Hood, K. Tatsukawa, L. Heifetz, and S. Wachsmann-Hogiu, 鈥淪ingle-step preparation and image-based counting of minute volumes of human blood鈥, Lab on a Chip, 14 (16), 2014, pp. 3029-3036.
  29. M. A. S. de Oliveira, Z. J. Smith, F. Knorr, R. E. de Araujo, and S.Wachsmann-Hogiu, 鈥淟ong Term Raman Spectral Study of Power-Dependent Photodamage in Red Blood Cells鈥, Applied Physics Letters, 104, 2014, 103702.
  30. M. Kahraman, P. Daggumati, O. Kurtulus, E. Seker, S. Wachsmann-Hogiu, 鈥淔abrication and Characterization of Flexible and Tunable Plasmonic Nanostructures鈥, Scientific Reports 3, 2013: 3396 | DOI: 10.1038/srep03396.
  31. T. Zhang, S. Osborn, C. Brandow, D. Dwyre, R. Green, S.M. Lane, S. Wachsmann-Hogiu, 鈥Structured Illumination-Based Super-Resolution Optical Microscopy for Hemato- and Cyto-Pathology Applications鈥, Analytical Cellular Pathology, 36 (1) 2013, pp. 27-35.
  32. M. Kahraman , B.N. Balz and S. Wachsmann-Hogiu, 鈥淗ydrophobicity-driven self-assembly of protein and silver nanoparticles for protein detection using surface-enhanced Raman scattering鈥, Analyst, 138 (10), 2013, pp. 2906-2913.
  33. Z. J. Smith, T. R. Huser, S. Wachsmann-Hogiu, 鈥淩aman scattering in pathology鈥, Analytical Cellular Pathology, 2012, 35 (3), pp. 145-163.
  34. Z. J. Smith, C.-W. Chang, L. S. Lawson, S. M. Lane, S. Wachsmann-Hogiu, 鈥淧recise Monitoring of Chemical Changes through Localization Analysis of Dynamic Spectra (LADS),鈥 Applied Spectroscopy, 67(2), 2013, pp. 187-195.
  35. Z. J. Smith*, K.Q Chu, S. Wachsmann-Hogiu, 鈥淣anometer-Scale Sizing Accuracy of Particle Suspensions on an Unmodified Cell Phone Using Elastic Light Scattering鈥, PLoSONE, Oct. 2nd 2012, 7(10), e46030.
  36. Z. J. Smith, S. Strombom, S. Wachsmann-Hogiu, 鈥淢ultivariate optical computing using a digital micromirror device for fluorescence and Raman spectroscopy鈥, Optics Express, 2011, Vol. 19, Issue 18, pp. 16950-16962.
  37. Z. J. Smith, K. Chu, A. R. Espenson, M. Rahimzadeh, A. Gryshuk, M. Molinaro, D. M. Dwyre, S. M. Lane, D. Matthews, S. Wachsmann-Hogiu, 鈥淐ell-phone-based platform for biomedical device development and education applications鈥, PLoSONE, 2011, 6(3): e17150.
  38. C. V. Pagba, S. M. Lane, S. Wachsmann-Hogiu, 鈥淐onformational changes in quadrulpex oligonucleotide structures probed by Raman spectroscopy鈥, Biomedical Optics Express, Vol. 2, Issue 2, 2011, pp. 207-217.
  39. F. Knorr, Z. J. Smith, S. Wachsmann-Hogiu, 鈥淒evelopment of a time-gated system for Raman spectroscopy of biological samples鈥, Optics Express, Vol. 18, No. 19, 2010, pp. 20049-20058.
  40. C. V. Pagba, S. M. Lane, H. Cho, S. Wachsmann-Hogiu, 鈥淒irect detection of aptamer-thrombin binding via surface-enhanced Raman spectroscopy鈥, J. Biomed. Opt., Vol. 15 (4), 2010, 047006.
  41. C. V. Pagba, S. M. Lane, S. Wachsmann-Hogiu, 鈥淩aman and SERS studies of the 15-mer DNA Thrombin Binding Aptamer鈥, Journal of Raman Spectroscopy, Vol. 41, Issue 3, 2010, pp. 241-247.
  42. S. Wachsmann-Hogiu, T. Weeks, T. Huser, 鈥淐hemical analysis in vivo and in vitro Raman spectroscopy 鈥 from single cells to humans鈥, Curr. Opinions in Biotech., Vol. 20, 2009, pp. 63-73
  43. S. Wachsmann-Hogiu, L. A. Peteanu, L. A. Liu, D. J. Yaron, J. Wildeman, 鈥淭he Effects of Structural and Micro- Environmental Disorder on the Electronic Properties of MEH-PPV and Related Oligomers鈥, J. Phys. Chem. B, vol. 107, 2003, pp. 5133-5143.
  44. S. Wachsmann-Hogiu, W. Werncke, J. Dreyer, A. I. Vodchits, K.-W. Brzezinka, 鈥淯ltrafast intramolecular electron transfer studied by stationary vibrational and time-resolved resonance Raman spectroscopy combined with ab initio calculations鈥, Recent Res. Devel. Chem. Physics, Vol. 2, 2001, pp. 83-106.
  45. S. Hogiu, J. Dreyer, M. Pfeiffer, K.-W. Brzezinka, W. Werncke, 鈥淰ibrational analysis and excited-state geometric changes of betaine-30 derived from Raman and infrared spectra combined with ab initio calculations鈥, J. Raman Spectrosc., Vol. 31, Issue 8/9, 2000, pp. 797-803.
  46. S. Hogiu, W. Werncke, M. Pfeiffer, J. Dreyer, T. Elsaesser, 鈥淢ode-specific vibrational excitation and energy redistribution after ultrafast intramolecular electron transfer鈥, J. Chem. Phys., Vol. 113, Issue 4, 2000, pp. 1587-1594.
  47. S. Hogiu, W. Werncke, M. Pfeiffer, T. Elsaesser, 鈥淢ode specific vibrational kinetics after intramolecular electron transfer studied by anti-Stokes Raman spectroscopy鈥, Chem. Phys. Lett., Vol. 312, Issue 5-6, Oct. 1999, pp. 407-414.
  48. S. Hogiu, W. Werncke, M. Pfeiffer, A. Lau, 鈥淓vidence of strong vibronic coupling in the first excited singlet state of diphenylhexatriene by picosecond CARS spectroscopy鈥, Chem. Phys. Lett., Vol. 303, Issue 1-2, 2 April 1999, pp. 218-222.
  49. S. Hogiu, W. Werncke, M. Pfeiffer, A. Lau, T. Steinke, 鈥淧icosecond time-resolved CARS spectroscopy of a mixed excited singlet state of diphenylhexatriene鈥, Chem. Phys. Lett., Vol. 287, Issue 1-2, 24 April 1998, pp. 8-16.
  50. M.L. Pascu, B. Carstocea, G. Popescu, O. Gafencu, S. Apostol, N. Moise, M. Roman, S. Hogiu, 鈥淚maging corneal cells using low power beams鈥, Lasers in Medical Science, Vol. 13, Issue 2, 1998, pp. 148-154.
  51. S. Hogiu, M. Enescu, M.L. Pascu, 鈥淒ynamic and thermodynamic effects of glycerol on bovine serum albumin in aqueous solution: a tryptophan phosphorescence study鈥, J. of Photochem.Photobiol. B: Biology, Vol. 40, Issue 1, Aug. 1997, pp. 55-60.
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