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Ramping up research

After a long period away from the lab, life is slowly reaching a new normal

Over the course of five days in March, Tom Durcan鈥檚 lab at The Neuro went from a bustling centre of neuroscience research to almost complete shutdown, an experience he shares with the rest of The Neuro鈥檚 principal investigators. Restrictions on research are gradually being lifted at The Neuro, but the effects of the pandemic will be felt for a long time.

Durcan鈥檚 team of 45 research staff and trainees working at the lab at any given time fell to a skeleton staff of seven people, who came in to make sure the freezers were working and liquid nitrogen tanks were filled. The focus became preserving the stem cell research they had ongoing rather than moving it forward. They froze down cell lines to continue growing them later. Lab members worked on data and protocols from home, and the lab held regular meetings virtually to coordinate or just stave off the social isolation.

Now the team is running at 75 per cent of normal capacity, with more members coming to the lab regularly. They have a shift system in place so everyone has enough room to keep physical distance. Staff wear masks and extra hand sanitation and other measures are now in place.

Durcan says they were lucky that some projects were near completion when the shutdown began, although they had to put a number of other projects on hold for now. While things are gradually returning to normal, Durcan says they will hopefully take many lessons from this pandemic, including operating the lab with more flexible schedules.

鈥淚t gave us some time reflect on things, how we were doing things, how can we improve, maybe how we can do science more efficiently,鈥 he says. 鈥淚t would be nice to come back to some sense of normalcy, but maybe we learned some things we can use in our new day to day routine. Maybe instead of everyone in at the same time, some will work in the AM, and others in the PM, creating more flexible schedules and more options for how and when staff can work.鈥

Pandemic disruption has been 鈥渄evastating鈥 for some

The pandemic also disrupted the routine of Ed Ruthazer and his lab members, who study brain development at the cellular level using fish and frogs. Ruthazer says the shutdown is 鈥渄evastating鈥 for researchers who were one or two experiments away from writing a paper. Researchers with children are also disproportionately impacted due to the shutdown of schools and daycares.

Yet some others have used the extra downtime to focus on writing or analyzing data. His lab has learned to use online programs such as Slack and Zoom to stay in touch remotely. At any one time, he says he may have up to nine programs open to talk to his staff.

Ruthazer keeps his lab at half capacity to maintain physical distance, and slowly things are returning to normal. He credits The Neuro鈥檚 Centre for Neurological Disease Models for looking after their fish and frogs during the pandemic.

While the ramp up is ongoing, questions remain. Ruthazer says he is not sure if he can hire new researchers for September, given the travel and physical distancing restrictions still in place, not just in Canada but around the world. Ruthazer says this causes more problems for the students than him, because they are the ones who have to arrange visas, apartments and plane tickets.

He was also concerned that the shutdown could have financial consequences for his current lab members, because many of them are being paid through grants and fellowships. Ruthazer says he was happy to hear that Canada鈥檚 three granting agencies would for researchers in certain programs by four months to allow researchers to make up for lost time.

On the week of June 22, The Neuro and 91社区 began Phase 3 of its research ramp up process. to learn more about COVID-19 safety guidelines at 91社区 and at The Neuro.

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The Neuro (Montreal Neurological Institute-Hospital)听is a bilingual academic healthcare institution. We are a听91社区 research and teaching institute; delivering high-quality patient care, as part of the Neuroscience Mission of the 91社区 Health Centre.听We are听proud to be a Killam Institution, supported by the Killam Trusts.

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