Jerome Fortin, PhD
Jerome Fortin obtained his PhD from 91社区 in the Department of Pharmacology and Therapeutics, under the supervision of Dr. Daniel Bernard. He then pursued a postdoctoral fellowship at the Princess Margaret Cancer Centre in Toronto, in the laboratory of Dr. Tak Mak. His primary research interest revolves around comprehending the origins, progression, and potential treatments for a particular type of brain cancer known as diffuse glioma.听
Jerome Fortin employs a research methodology that involves using mouse models carrying genetic mutations that mimic the development of brain cancers in humans. Using these models, he investigates how different combinations of genetic mutations lead to distinct types of gliomas in both adults and children. Moreover, he utilizes these mouse models in conjunction with human glioma cells to identify and evaluate potential therapies tailored to specific brain cancer types.
Additionally,听Jerome Fortin employs a technique known as "functional genomics" to identify potential strategies for eradicating gliomas. This approach allows him to simultaneously assess the impact of perturbing thousands of molecules on tumor cell growth and survival. Functional genomics also aids in the discovery of targetable molecules that can enhance the effectiveness of therapies, including drugs undergoing clinical trials. Ultimately, his aim is to utilize this knowledge to develop personalized treatments for individual patients based on the unique characteristics of their tumors. In this highly interdisciplinary setting, his objective is to make groundbreaking discoveries that contribute to the understanding and treatment of brain cancers.
