Thomas Gabriel Leonard, PhD
Affiliate Member
Gabriel Leonard is a clinical scientist and he coordinates the MNH neuropsychology outpatient service. Current research projects include: examining the long-term consequences of prenatal exposure to maternal cigarette smoking on brain structure, function and mental health in adolescence, Longitudinal study of brain maturation and cognitive development in teenagers combining several brain mapping approaches (collaboration with Tomas Paus) & Magnetic resonance imaging of multiple sclerosis and associated cognitive profiles (collaboration with Doug Arnold and Louis Collins). Leonard is active in test development and is establishing normative data for a new computerized device to measure simple and complex hand and arm movements (N=2000). He is collaborating with Drs Clarke, Pike and Appenzeller to examine the cognitive consequences of systemic Lupus.
Neuropsychology
Cognitive Neuroscience
Neuroimaging and Neuroinformatics
Waber, D.P., deMoor, C., Forbes, P.W., Almli, C.R., Botteron, K.N, Leonard, G., Milovan, D., Paus, T., Rumsey, J., and the Brain Development Cooperative Group (2007). The NIH MRI Study of Normal Brain Development: Performance of an epidemiologically ascertained sample of healthy children aged 16 to 18 Years on a neuropsychological battery. Journal of the International Neuropsychological Society, 13(5):729-46.
Toro R, Leonard G, Lerner JV, Lerner RM, Perron M, Pike GB, Richer L, Veillette S, Pausova Z and Paus T. Prenatal Exposure to Maternal Cigarette Smoking and the Adolescent Cerebral Cortex. Neuropsychopharmacology, 35(5):1019-27, 2007.
Paus T, Nawazkhan I, Leonard G, Perron M, Pike GB, Pitiot A, Richer L, Veillette S, Pausova Z. Corpus callosum in adolescent offspring exposed prenatally to maternal cigarette smoking. Neuroimage. 2007.
Grosbras, MH, Jensen, M, Leonard, G, McIntosh, A, Osswald, K, Poulsen, C, Steinberg, L, Toro, R, Paus T. Neural Mechanisms of Resistance to Peer Influence in Early Adolescence. The Journal of Neuroscience, July 25, 2007 • 27(30):8040 – 8045.
Pausova, Z, Paus, T, Abrahamowicz, M, Almerigi, J., Arbour, N., Bernard, M., Gaudet, D., Hanzalek, P., Hamet P., Evans, A.C., Kramer, M. Laberge, L, Leal S., Leonard, G., Lerner, J. Lerner RM, Mathieu, J. Perron, M., Pike, B., Pitiot, A., Richer, L, Séguin, J.R. Syme, C. Toro, R., Tremblay, R.E., Veillette, S. & Watkins, K. Genes, Maternal Smoking, and the Offspring Brain and Body During Adolescence: Design of the Saguenay Youth Study. Human Brain Mapping 28:502–518 (2007).
Paus, T., Toro, R., Leonard, G., Lerner, J., Lerner, R.M., Perron, M., Pike, G.B., Richer, L., Steinberg, Veillette, S., Pausova, Z. Morphological properties of the action-observation cortical network in adolescents with low and high resistance to peer influence. Social Neuroscience, DOI: 10. 1080/17470910701563558; First Published on: 20 September 2007.
Jansen, A.C., Cao, H., Kaplan, P., Silver, K., Leonard, G., De Meirleir, L., LIssens W., Leibaers, I. Veilleux, M., Andermann, F., Hegele, R.A. & Andermann, E. Sanfilippo syndrome type D: natural history and identification of 3 novel mutations in the GNS Gene. Arch. Neurol., 64(11): 1629-34, 2007).
Perrin, J.S., Hervé, P.Y., Leonard, G., Perron M., Pike G.B., Pitiot, A., Richer, L., Veillette, S., Pausova, Z., Paus T. Growth of white matter in the adolescent brain : role of testosterone and androgen receptor. J. Neuroscience, 28(38): 9519:24, 2008. Syme, C. Abrahamowicz, M., Leonard, G., Pitiot, A., Perron, M., Qiu, X., Richer, L., Totman, J. Veillette, V., Gaudet, D., Paus, T. & Pausova, Z. Intra-abdominal adiposity and the metabolic syndrome in adolescence: Gender differences and underlying mechanisms. Archives of Pediatrics & Adolescent Medicine, 162(5):453-61. In Press.