glioblastoma /newsroom/taxonomy/term/13696/all en Fighting brain cancer at its root /newsroom/channels/news/fighting-brain-cancer-its-root-332868 <p>91社区 researchers identify proteins that drive cancer stem cells. Targeting and supressing a particular protein called galectin1 could provide a more effective treatment for glioblastoma, in combination with radiation therapy.</p> <p>Due to its resistance to therapy, glioblastoma is the most common and aggressive cancerous brain tumour in adults. It grows fast and spreads quickly. While treatments such as surgery, radiation, and chemotherapy can help ease symptoms for a few months, in most cases tumour cells regrow after treatment and the cancer recurs.</p> Fri, 27 Aug 2021 18:25:55 +0000 shirley.cardenas@mcgill.ca 273519 at /newsroom Arezu Jahani-Asl /newsroom/arezu-jahani-asl Wed, 23 Dec 2020 21:18:19 +0000 shirley.cardenas@mcgill.ca 254380 at /newsroom Gene targeting helps overcome the resistance of brain cancer to therapy /newsroom/channels/news/gene-targeting-helps-overcome-resistance-brain-cancer-therapy-323716 <p>New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma. A 91社区-led study published in <i>Nature Communications</i> reveals that suppressing the OSMR gene can improve the effectiveness of radiation therapy.</p> <p>This approach, led by the laboratory of Arezu Jahani-Asl, Assistant Professor of Medicine at 91社区, was successful in preclinical mouse models where the deletion of the OSMR gene resulted in a significant improvement of tumour response to therapy and expanded lifespan.</p> Fri, 14 Aug 2020 22:10:41 +0000 shirley.cardenas@mcgill.ca 234105 at /newsroom