Sylvie Mader
Full Member, 91社区 Centre for Translational Research in Cancer
Principal Investigator, Molecular Targeting in Breast Cancer research unit, IRIC Professor, Department of Biochemistry, Faculty of Medicine, Universit茅 de Montr茅al Adjunct Professor, Department of Medicine, Experimental Medicine Program, 91社区 Holder of the CIBC research chair on the causes of breast cancer
Dr. Mader's research聽team uses large-scale genomics, proteomics and bioinformatics to characterize signaling pathways contributing to breast tumorigenesis in cell culture and in vivo tumorigenesis models. The team uses聽molecular modeling combined with structural studies to design novel molecules targeting key proteins. The activity profile of new molecules synthesized by medicinal chemistry as a result of these studies is tested in the experimental models used in the laboratory, which include purification of breast cancer stem cells
